Microfluidic Microchannel (Size And Shape) for Single Cell Analysis by Numerical Optimization: Lateral Trapping Method
Sushmitha. M1, Jasper James. A2, Vigneswaran Narayanamurthy3, Padmasini .N4, Fahmi Samsuri5
1Sushmitha M, Department of Biomedical Engineering, Kalasalingam Academy of Research and Education College, Virudhunagar (Tamil Nadu), India.
2Jasper James A, Innofutech, Chennai (Tamil Nadu), India.
3Vigneswaran Narayanamurthy, Department of Electrical and Electronic Engineering Technology, Universiti Teknikal Malaysia.
4Padmasini N, Department of Biomedical Engineering, Rajalakshmi Engineering College, Chennai (Tamil Nadu), India.
5Fahmi Samsuri, Department of Electrical and Electronics Engineering, University Malaysia Pahang Pekan, Pekan, Pahang Malaysia.
Manuscript received on 24 November 2019 | Revised Manuscript received on 18 December 2019 | Manuscript Published on 30 December 2019 | PP: 747-752 | Volume-9 Issue-1S4 December 2019 | Retrieval Number: A11361291S419/19©BEIESP | DOI: 10.35940/ijeat.A1136.1291S419
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© The Authors. Blue Eyes Intelligence Engineering and Sciences Publication (BEIESP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Abstract: The primary objective of this work is to show simulation outputs from the developed model of cell flow within a microfluidic device. This work is essential because it requires computational models to offer compact sized biomedical equipment that involves microfluidics technology. Microfluidics has become a common technology for life science applications in latest years. The purpose is to learn the effect of various microchannel size and shape with lateral traps for single cell analysis and to arrive at an optimum design based on a simulation study using COMSOL Multiphysics software. Thus in order to develop software model of various microchannels which execute fluid flow in the microelectronic device. This research provides numerical alternatives from finite element analysis simulation using the software COMSOL-Multiphysics to characterize the shape and size of the microchannel initializing the fluid flow. Optimized design analysis and operating conditions for efficient single cell trap is reported.
Keywords: COMSOL, Microchannel, Microfluidics, Simulation, Single Cell, Trapping.
Scope of the Article: Data Mining Methods, Techniques, and Tools